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Targeting a solid design for prostheses

A thesis drafted jointly by Cetim, Southampton University and Simpleware Ltd has opened up a new methodology for the design of implants able to match variation in the human body.

 

The anatomic characteristics of each member of a population differ! This may appear obvious, but on this basis, it is difficult to establish standard mechanical systems such as medical devices. This complex situation is particularly relevant during the manufacturing process (e.g. wide range of surface conditions generated by the process) and when using these implants. Incorporating variation in the configurations of living beings from the design phase is mandatory if we intend to manage the performance and reliability of products. This is the basis for a solid design. It was therefore necessary to enable the development of a methodology for the purposes of designing optimised implants compatible with variation in living beings. The study carried out by the trio consisting of Cetim, Southampton University and Simpleware Ltd was completed in 2015. The R&D project therefore led to the launch of an optimisation process, based on a reference panel of 109 patients, for the design of femoral implants… Leading to enhanced performance (primary stability).

 

The study is being continued

The methodology proposed is based, among other factors, on statistical models representing variation (morphology, bone quality, etc.); numerical tools to model mechanical behaviour; and other tools to analyse and use results and optimise as necessary, etc. Thanks to the works, a virtual population of 1000 femur geometries was automatically generated, in particular. This provided precious assistance in selecting an implant depending on the patient!

Finally, these results can be used to obtain a glimpse of major benefits for the development of future implants relating to new imaging and manufacturing technologies, enabling customised products… Over and beyond this aspect, this methodology brings other options such as the integration of fatigue-based aspects when assisting with design… the focus of the rest of this study.

(06/23/2016)

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